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目的:对氨苄青霉素胶囊的溶出度测定方法进行了研究,确立。方法:采用青霉烯酸比色法测定其溶出量。结果:平均回收率为101.2%,RSD 为0.5%(n=9),在15～35μg·ml~(-1)范围内线性关系良好。结论:本法简便,可靠,可用于氨苄青霉素胶囊的溶出度测定。
Objective: To determine the dissolution of ampicillin capsules was established. Methods: Penehyclidate colorimetry was used to determine the dissolution rate. Results: The average recovery was 101.2% with a RSD of 0.5% (n = 9). The linearity was good in the range of 15 ~ 35μg · ml ~ (-1). Conclusion: This method is simple and reliable and can be used for the determination of dissolution of ampicillin capsules.