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作者对17例有典型库兴氏综合征临床表现的患者作了不同方式的地塞米松抑制试验、甲吡酮试验以及血浆ACTH测定等项检查,根据综合分析、手术、病理以及治疗随访等项结果,17例最后诊断及其例数分布如下:柯兴氏病13例、肾上腺皮质肿瘤3例(腺癌2,腺瘤1)及异性ACTH综合征1例(支气管类癌)。作者着重对夜间大剂量地塞米松抑制试验(8mg晚11时一次口服,测定服药前后上午8时的血浆皮质醇)和经典大剂量地塞米
The authors examined 17 patients with typical Cushing’s syndrome clinical manifestations of dexamethasone suppression test, metyrapone test and plasma ACTH determination of other patients, according to comprehensive analysis, surgery, pathology and treatment follow-up and other items Results: The final diagnosis of 17 cases and their distribution were as follows: 13 cases of Cushing’s disease, 3 cases of adrenocortical tumors (adenocarcinoma 2, adenoma 1) and 1 case of heterosexual ACTH syndrome (bronchial carcinoid). The authors focused on the nighttime high-dose dexamethasone suppression test (8 mg once daily at 11 o’clock orally, measured at 8 am before and after administration of plasma cortisol) and classic high-dose dex