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目的 :选择处在肺炎球菌感染高危期的人群 ,接种现行推荐的肺炎球菌多糖疫苗 ,之后测定疫苗的效果 ,评价疫苗的保护期限。实验设计 :在 14年期间用间接群体分析法进行了全国监测未接种疫苗者及接种疫苗者之中受到与疫苗中相同血清型的肺炎球菌感染的病人比例 ,以评价疫苗的效果
OBJECTIVE: To select the population of pneumococcal high-risk patients who were vaccinated with the current recommended pneumococcal polysaccharide vaccine, measure the efficacy of the vaccine and evaluate the duration of protection. Experimental Design: The proportion of patients infected with pneumococci in the same serotypes in vaccines among those who were unvaccinated and vaccinated during the national surveillance over a 14-year period was assessed by indirect group analysis to evaluate the vaccine’s efficacy