【摘 要】
：
目的研究二核苷酸重复序列不稳定性〔DRSI〕在胃癌发生中的作用及其临床意义.方法采用PCR方法检测了D17S261和D17S799位点二核苷酸重复序列不稳定性.结果胃癌总DRSI发生率为3
【机 构】
：
解放军322医院内一科;第三军医大学西南医院消化科
论文部分内容阅读
目的研究二核苷酸重复序列不稳定性〔DRSI〕在胃癌发生中的作用及其临床意义.方法采用PCR方法检测了D17S261和D17S799位点二核苷酸重复序列不稳定性.结果胃癌总DRSI发生率为34％(17/50),其中高中分化腺癌DRSI阳性率(66?7％,10/15)显著高于低分化癌(19?4％,6/31,P＜0?01);肠型胃癌DRSI阳性率(55?6％,10/18)显著高于胃型胃癌(20％,6/30,P＜0?05),DRSI与胃癌部位、大小、浸润、分期、淋巴结转移无显著相关.结论DRSI在胃癌的发生中可能起重要作用.“,”AIM To investigate dinucleotide repeat sequence instability (DRSI) in the carcinogenesis of gastric cancer. METHODS DRSI was detected in 50 surgically resected specimens of gastric cancer using the PCR method. RESULTS DRSI was detected in 17 (34 0%) of the 50 gastric cancer specimens. The frequency of DRSI in well differentiated gastric cancer (66 7%, 10/15) was significantly higher than that in poorly differentiated one (19 4%,6/31) ( P
其他文献
请下载后查看，本文暂不支持在线获取查看简介。
Please download to view, this article does not support online access to view profile.
百分之九十的大型鱼类与人们告别了。科学家们正在努力搞清这种情况的副作用究竟会是什么。
Ninety percent of large fish bid farewell to people. Scientists are trying
用FLUO?3?AM荧光探针和流式细胞术检测活性胰腺泡细胞内游离钙离子?刘仁则秦仁义SUBJECTHEADINGSPANCREATILIS;PANCREAS;CALCIUM/ANALY?SIS;FLOWCYTOMETRY;RATS主题词胰腺炎;
胃肠病中西医结合研究工作若干问题?赵荣莱SUBJECTHEADINGSGASTROINTESTINALDISEASES;INTEGRATEDTCM?WM;SPLEEN?STOMACHTHEORY;SPLEEN?STOMACHDISEASES主题词胃肠...
Indian Central Water (ICW) and Subantarctic Mode Water (SAMW) formation rates are estimated from two air-sea flux products, the Comprehensive Ocean-Atmosphere D
请下载后查看，本文暂不支持在线获取查看简介。
Please download to view, this article does not support online access to view profile.
十二指肠溃疡患者血清促胃液素水平与HP的相关性?王婉梅1陈垦1陈元鸿1王皓1揭育丽2SUBJECTHEADINGSDUODENALULCER/BLOOD;GASTRINS/BLOOD;HELICOBACTERPYLORI;HELICOBACTERIN.
抗癌药泵局部灌注治疗中晚期胃癌20例?褚东明黄凯平SUBJECTHEADINGSSTOMACHNEOPLASMS/DRUGTHERAPY;LIVERNEOPLASMS/SECONDARY;PANCREATICNEOPLASMS/SECONDARY;A...