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皮肤粘膜念珠菌病大体有两种类型:1.严重的全身性念珠菌病亦称慢性皮肤粘膜念珠菌病;2.常见限局的普通念珠菌病。近来经研究后对慢性皮肤粘膜念珠菌病有了更进一步的了解,可侵犯皮肤、口腔、粘膜、上呼吸道、胃肠道及尿道和阴道上皮,但尽管感染广泛,并不见真菌血症。大多数患者有细胞免疫缺陷而体液免疫则显然正常,有时有内分泌异常或胸腺障碍。电子显微镜的观察证实,白色念珠菌可侵犯皮肤粘膜的表皮上层细胞,真菌能够穿破上皮细胞的浆膜并进
Skin mucosal candidiasis in general there are two types: 1. Severe systemic candidiasis is also known as chronic cutaneous mucosal candidiasis; 2. common limit of the common candidiasis. Recent studies have shown a better understanding of chronic mucocutaneous candidiasis and can invade the skin, mouth, mucous membranes, upper respiratory tract, gastrointestinal tract and urethra and vaginal epithelium, but no fungal sepsis is seen despite the widespread infection. Most patients have cellular immune deficiency and humoral immunity is clearly normal, and sometimes endocrine abnormalities or thymus disorders. Observation by electron microscopy confirmed that Candida albicans could invade the epidermal cells of the skin and mucous membranes and that the fungi could penetrate the serosal epithelial cells