砷引起机体氧化与抗氧化代谢失衡是重要的毒作用机制之一。生理情况下,体内存在着的抗氧化防御系统在一定程度上能防止脂质过氧化(lipid peroxidation,LP)的发生,使机体自由基的产生与清除处于平衡状态。当实验动物或病区人群摄入较多砷化物时导致机体产生过量自由基,机体抗氧化防御系统与其抗 Arsenic cause body oxidation and antioxidant metabolism imbalance is one of the important mechanisms of toxicity. Physiologically, the body’s antioxidant defense system to a certain extent, to prevent the occurrence of lipid peroxidation (LP), so that the body’s production and clearance of free radicals in balance. When the experimental animals or ward population intake of more arsenic when the body produces excessive free radicals, the body’s antioxidant defense system and its resistance