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目的:探讨临床检测血清肌钙蛋白Ⅰ及肌红蛋白含量对诊断妊娠高血压综合征的应用价值。方法:选取40例妊娠高血压患者作为研究对象,采用免疫荧光分析仪对患者的血清肌钙蛋白Ⅰ和肌红蛋白含量进行临床检测分析,另外选取40例正常孕妇,测定其肌钙蛋白Ⅰ和肌红蛋白含量。结果:妊高征伴蛋白尿组cTnⅠ、Mb水平和妊高征无蛋白尿组及正常组比较具有显著性差异(P<0.05),妊高征无蛋白尿组和正常组比较无显著性差异(P>0.05)。妊高征伴有蛋白尿组各个时段cTnl含量明显高于妊高症无蛋白尿和正常组(P<0.05),且cTnl含量在各个时段并无明显变化,比较不具有显著性差异(P>0.05)。结论:早期通过cTnl和Mb的检测评估PIH孕妇心肌损害,能够及时发现并对心肌损伤程度进行监测,对PIH孕妇的治疗以及预后的判断具有重大的意义。
Objective: To investigate the clinical value of serum troponin I and myoglobin in the diagnosis of pregnancy induced hypertension syndrome. Methods: Forty pregnant women with pregnancy-induced hypertension were enrolled in this study. Serum levels of troponin I and myoglobin were detected by immunofluorescence analyzer. Forty normal pregnant women were selected and their troponin I and Myoglobin content. Results: The levels of cTnⅠ and Mb in PIH group were significantly different from those in normal group (P <0.05). There was no significant difference in proteinuria group and PIH group (P> 0.05). The content of cTnl in each stage of PIH with proteinuria was significantly higher than that of normal pregnancy (P <0.05), and the content of cTnl did not change significantly at all time points, with no significant difference (P> 0.05). CONCLUSION: Early detection of myocardial damage in PIH pregnant women by early detection of cTnl and Mb can be timely detected and the degree of myocardial injury is monitored, which is of great significance for the treatment and prognosis of PIH pregnant women.