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目的探讨中西医结合治疗不稳定型心绞痛患者(unstable angina pectoris)对凝血指标的影响及临床疗效。方法随机选择不稳定型心绞痛患者100例,分为中西医结合组50例和常规治疗组50例,常规治疗组采用硝酸甘油、倍他乐克和阿司匹林等传统西医治疗,中西医结合组在常规治疗组基础上加用黄芪注射液静滴14d,观察两组患者凝血指标水平的变化以及心绞痛及心电图疗效。结果中西医结合组血纤维蛋白原、血小板平均体积血血小板分布密度低于常规治疗组,血小板数量水平高于常规治疗组(分别为P<0.05、P<0.05、P<0.05、和P<0.05),心绞痛及心电图疗效高于常规治疗组(分别为P<0.05和P<0.05)。结论与常规西医治疗相比,中西医结合治疗不稳定型心绞痛能明显改善异常凝血状态,临床疗效更好,是不稳定型心绞痛较好的治疗方法。
Objective To investigate the effect of unstable angina pectoris on coagulation parameters and its clinical efficacy in the treatment of traditional Chinese and western medicine. Methods A total of 100 patients with unstable angina pectoris were randomly selected. The patients were divided into traditional Chinese and western medicine group (n = 50) and conventional treatment group (n = 50). The conventional treatment group was treated with traditional western medicine such as nitroglycerin, metoprolol and aspirin. On the basis of the treatment group, Astragalus injection was intravenously administered for 14 days to observe the change of coagulation index and angina pectoris and electrocardiogram in both groups. Results The density of fibrinogen and platelet-derived platelet in the TCM-WM group was lower than that in the conventional treatment group, and the platelet count was higher than that in the conventional treatment group (P <0.05, P <0.05, P <0.05, ), Angina pectoris and electrocardiogram higher than the conventional treatment group (P <0.05 and P <0.05, respectively). Conclusion Compared with conventional western medicine, the treatment of unstable angina pectoris with traditional Chinese medicine and western medicine can significantly improve the abnormal coagulation state and has better clinical curative effect. It is a better treatment for unstable angina pectoris.