头孢噻肟钠是第三代头孢菌素,抗菌谱广,对大肠埃希菌、奇异变形杆菌、克雷伯菌属和沙门菌属等革兰阴性肠杆菌作用突出,毒性低,对β内酰胺酶稳定,对厌氧菌的抗菌活性较弱。因此在可能存在混合感染的情况下临床常将头孢噻肟钠与具有抗厌氧菌活性的药物联用,其中以奥硝唑、甲硝唑居多。本文分析了1例阑尾切除术后患者使用头孢噻肟钠联合奥硝唑氯化钠注射液进行抗感染治疗时药液变红的现象,现报道如下。1病例简介 Cefotaxime sodium is the third generation cephalosporin, broad antibacterial spectrum of Escherichia coli, Proteus mirabilis, Klebsiella and Salmonella Gram-negative Enterobacteriaceae prominent, low toxicity, β Amidase stability, antimicrobial activity of anaerobic bacteria is weak. Therefore, in the case of possible mixed infections, cefotaxime sodium is often used in combination with anti-anaerobic drugs, with ornidazole and metronidazole being mostly used. This article analyzes a case of appendectomy patients using cefotaxime sodium ornidazole sodium chloride injection for anti-infection liquid reddening phenomenon, are reported below. 1 case brief introduction