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乳腺导管原位癌(DCIS)其组织学特征是恶性肿瘤细胞仅局限于乳腺导管,光镜下未见癌细胞穿透基底膜侵犯周围组织。近20年来,欧美DCIS的发生率增加了10倍以上,对伴有微小钙化灶的乳腺进行诊断性活检,DCIS的发病率为20％～25％,发生率的增大最大可能是对高危人群广泛使用乳腺X线照相技术做普查,并对有可疑征象者行细针活检有关;同时也可能与乳腺疾病的组织病理学诊断标准
The histological features of ductal carcinoma in situ (DCIS) is that the malignant tumor cells are only confined to the mammary duct. Under light microscope, no cancer cells penetrate the basement membrane and invade the surrounding tissues. In the past 20 years, the incidence of DCIS in Europe and the United States has increased more than 10 times. Diagnostic biopsies have been performed on mammary glands with microcalcifications. The incidence of DCIS is 20% to 25%, and the increase in the incidence rate is most likely to be associated with high-risk groups. Extensive use of mammography techniques for census, and related to fine needle biopsy in suspicious signs; it may also be associated with histopathological diagnostic criteria for breast disease