1病例资料患者,女,64岁,体质量65 kg,2天前因四肢、手背部皮肤红肿,夜间瘙痒严重,不能入睡,于2015年5月29日来我院皮肤科就诊。体检:T 36.5℃,P 80次/min,R 20次/min,BP 125/82 mm Hg。实验室检查:肝肾功能正常。双上肢前臂呈小片红斑、双下肢小腿前侧及手背部散在针尖样大丘疹,手脚部位皮肤干燥起皮。既往无糖尿病、肾病、肝病、肿 1 case data, female, 64 years old, body weight 65 kg, 2 days ago due to limbs, hand back and skin irritation, severe itching at night, can not sleep, on May 29, 2015 to our hospital dermatology clinic. Physical examination: T 36.5 ° C, P 80 beats / min, R 20 beats / min, BP 125/82 mm Hg. Laboratory tests: normal liver and kidney function. Upper extremity forearm was small erythema, both lower extremity calf anterior and back scattered in the tip-like papules, dry skin and hands and feet skin. Past no diabetes, kidney disease, liver disease, swollen