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目的了解非淋菌性尿道炎解脲支原体感染状况及其耐药性,指导临床合理用药。方法采用分离鉴定和药敏试验方法,对某医院泌尿外科和妇科门诊患者送检标本进行检测与结果分析。结果该医院在2010-2012年期间,从733份患者送检标本中检出解脲支原体174株,检出率为23.7%。解脲支原体感染患者中,女性占76.4%,男性占23.6%;年龄21岁~40岁感染率构成比为67.2%。临床分离的解脲支原体对交沙霉素、多西霉素、四环素、米诺霉素等常用抗菌药物均比较敏感,但对环丙沙星呈现出耐药倾向。结论女性和中青年是解脲支原体感染高发人群,其对常用抗菌药物比较敏感,应慎用喹诺酮类药物。
Objective To understand the non-gonococcal urethritis ureaplasma urealyticum infection status and drug resistance, and guide the rational use of drugs. Methods The methods of isolation and identification and drug susceptibility testing were used to detect and analyze the specimens of urology and gynecology outpatients in a hospital. Results During the period from 2010 to 2012, the hospital detected 174 strains of Ureaplasma urealyticum from 733 samples, the detection rate was 23.7%. Ureaplasma urealyticum infection in patients, accounting for 76.4% of women, men accounted for 23.6%; age 21-40 years old infection rate of 67.2%. Ureaplasma urealyticum isolated clinically sensitive to josamycin, doxycycline, tetracycline, minocycline and other commonly used antimicrobial agents are sensitive, but showed ciprofloxacin resistance tendency. Conclusions Female and middle-aged and young people are high-risk population of Ureaplasma urealyticum infection. They are sensitive to the commonly used antibiotics and quinolones should be used with caution.