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20世纪40年代青霉素发现和临床应用后,使细菌性感染的治疗有惊人突破,以后各种高疗效的抗细菌抗生素相继发现,一些严重的细菌性疾病逐渐被控制。50年代认识到人和动物的某些严重疾病如脊髓灰白质炎、脑炎、流感、口蹄疫的病原是病毒,而对抗细菌抗生素又不敏感,寻找抗病毒抗生素的工作也受到注意。通过大量筛选,在50年代用动物、鸡胚从微生物发酵液和抗微生物的抗生素中找到一些在动物上有效的抗病毒抗生素如角膜干燥菌素(Xerosin),艾氏菌素(Ehrlichin),诺卡型霉素(Noformicin),
After the discovery and clinical application of penicillin in the 1940s in the 1940s, there have been astonishing breakthroughs in the treatment of bacterial infections. Since then, various highly effective anti-bacterial antibiotics have been successively discovered and some serious bacterial diseases have been gradually controlled. In the 1950s, it was recognized that some serious diseases of human beings and animals such as poliomyelitis, encephalitis, influenza and foot-and-mouth disease are viruses and are insensitive to antibiotic antibiotics. The search for antiviral antibiotics has also drawn attention. Through extensive screening, some animal antiviral antibiotics such as Xerosin, Ehrlichin, Neroli, Neroli, etc. have been found in animal and chicken embryos from microbial fermentation broths and antimicrobial antibiotics in the 1950s Noformicin,