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目的 检测不同部位消化道癌细胞内ER、PR水平 ,分析其与癌肿的发生及分化程度关系。方法 免疫组化检测采用SP法 ,试剂均为进口单克隆抗体 ,以统计标准观察ER、PR在细胞核的表达状态。结果 检测消化道癌共 4 6 3例 ,男 35 7例 ,女 10 6例 ,分别得出性别、癌肿发生部位、组织学类型、癌分化程度与ER、PR表达状态。结论 消化道癌中存在ER、PR ,且与癌肿发生部位、组织类型、分化程度有关。
Objective To detect the levels of ER and PR in different parts of digestive tract cancer cells, and to analyze their relationship with the occurrence and differentiation of cancer. Methods Immunohistochemical method using SP method, the reagents are imported monoclonal antibody to statistical standards ER, PR expression in the nucleus state. Results A total of 463 cases of gastrointestinal cancer were examined. There were 357 males and 106 females, and their gender, location of carcinomas, histological type, degree of cancer differentiation and expression of ER and PR were respectively obtained. Conclusion There are ER and PR in the digestive tract cancer, which are related to the site, type and differentiation of the cancer.