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目的:通过本研究,了解惠州地区儿童生长发育与血清维生素D(Vitamin D)、人生长激素(h GH)水平的关系。方法:随机采集2014年10月至2015年9月的不同年龄(0~10岁)和不同性别、表观健康的儿童的血液标本204例,离心分离血清,用罗氏全自动电化学发光法同时检测血清维生素D和人生长激素,记录检测结果并用SPSS进行统计学分析。结果:不同年龄组,男性和女性总维生素D检测结果之间比较,差异均无统计学意义(P>0.05),与厂家提供的欧美健康人群参考范围(>30 ng/m L)有着明显差别,普遍偏低。血清人生长激素在不同年龄和不同性别的儿童之间比较,差异具有统计学意义(P<0.05),且随着年龄的增长都呈下降趋势。结论:本研究结果说明总维生素D与年龄大小无关,而人生长激素浓度的高低与年龄和性别有关。是否可用同时检测总维生素D和人生长激素来衡量儿童的生长发育,有待进一步研究。
Objective: To understand the relationship between children’s growth and development, serum vitamin D and human growth hormone (hGH) in Huizhou area. Methods: Totally 204 blood samples were collected from October 2014 to September 2015 in children of different ages (0 ~ 10 years old) and of different gender and healthy children. The serum samples were separated by centrifugation and detected by Roche automatic electrochemiluminescence Serum vitamin D and human growth hormone were detected, the test results were recorded and analyzed by SPSS. Results: There was no significant difference in the total vitamin D test results between men and women in different age groups (P> 0.05), which was significantly different from the reference range (> 30 ng / m L) of the healthy adults in Europe and America , Generally low. Serum human growth hormone in children of different ages and genders, the difference was statistically significant (P <0.05), and with the increase of age showed a downward trend. Conclusion: The results of this study show that total vitamin D has nothing to do with age, while the concentration of human growth hormone is related to age and gender. The availability of simultaneous detection of total vitamin D and human growth hormone to measure children’s growth and development remains to be further studied.