1新靶标的期待与发现自身免疫性疾病是由于体内的免疫缺陷,导致机体不能容忍自身的蛋白,从而引发反应性疾病,这些疾病包括1型糖尿病、关节炎、牛皮癣和免疫性疾病等。如果药物能够对抗过于活跃的免疫系统,则可进行治疗或加以控制。而且,降低免疫系统的活性也是对器官移植防止排斥的必要手段。由于缺乏针对这些病因的治疗药物,临床治疗 Anticipation and Discovery of New Targets Autoimmune diseases are caused by the immune deficiency in the body, leading to the inability of the body to tolerate its own proteins, leading to reactive diseases such as type 1 diabetes, arthritis, psoriasis and immune diseases. Drugs can be treated or controlled if they are able to combat an overly active immune system. Moreover, reducing the activity of the immune system is also a necessary means of preventing rejection of organ transplants. Due to the lack of treatment for these causes of drugs, clinical treatment