论文部分内容阅读
目的:了解实验性脑出血边缘叶－海马区生长抑素(ＳＳ)应变效应。方法:用放免法测生长抑素。结果:远隔脑出血血肿部位的边缘叶－海马神经元,生长抑素含量明显增高,病理形态学显示海马神经元有高度水肿、变性、坏死的现象。结论:脑出血时除血肿直接压迫等造成其局部神经元的直接损害外,尚有远隔的边缘叶－海马神经元在神经内分泌调控紊乱介导作用下受到间接损害。
Objective: To understand the effect of somatostatin (SS) on the marginal leaf-hippocampus in experimental cerebral hemorrhage. Methods: To determine somatostatin by radioimmunoassay. Results: The marginal lobe-hippocampal neurons in the part of hematoma distal to hematoma significantly increased the content of somatostatin, and the pathomorphology showed hippocampal neurons were highly edema, degeneration and necrosis. Conclusion: In addition to the direct compression of hematoma caused by intracranial hematoma direct damage to local neurons, there are still distant edge of the leaf - hippocampal neurons in the mediation of neuroendocrine disorders under the indirect damage.