三分之二以上学龄前儿童在一段期间内至少患有一次急性化脓性中耳炎(AOM),其中约10%反复发作AOM(rAOM)。丙种球蛋白过低易罹患细菌感染,这一事实可部分解释为何AOM常见于生理性丙种球蛋白过低的个体,即年龄在6月到2岁半的儿童,但为什么某些儿童较另一些儿童易患中耳炎?对rAOM儿童和非中耳炎易感儿童研究后发现:rAOM者补体系统有畸变,血清中抗肺炎链球菌的特异性抗体浓度较低,随着年龄增长,这些差异消 Over two thirds of preschoolers have at least one acute suppurative otitis media (AOM) over a period of time, with about 10% recurrent AOM (rAOM). The fact that hypooglobulin is too low and susceptible to bacterial infections can partly explain why AOMs are common in individuals with hypogonadal hypogonadism, that is, children aged 6 months to 2 years and a half years, but why some children are more likely than others Children susceptible to otitis media? RAOM children and non-otitis media susceptible children study found: rAOM complement system has distortion, serum anti-pneumococcal specific antibody concentration is low, with age, these differences disappear