维生素D对骨具有两种作用,一方面促进骨基质形成和骨成熟,另一方面又增强破骨细胞活性并可能影响各种骨干细胞的分化。降钙素(CT)则能够抑制破骨细胞的活性从而减少骨吸收。因此,合用维生素D和CT可能会导致骨的正平衡。本文作者给绝经后骨质疏松妇女联合使用大剂量维生素 Vitamin D has two effects on bone, promoting bone matrix formation and bone maturation on the one hand, and osteoclast activity on the other and possibly affecting the differentiation of various bone marrow stem cells. Calcitonin (CT) can inhibit osteoclast activity and thus reduce bone resorption. Therefore, the combination of vitamin D and CT may lead to a positive bone balance. The authors combined high-dose vitamins with postmenopausal women with osteoporosis