本文分析6例镇静催眠药急性中毒死亡的临床症状,法医学尸检和毒物分析资料。镇静催眠药中毒临床表现为昏迷、呼吸抑制、低血压、反射消失、周围循环衰竭等。病理变化以肺、肝、肾、脑等脏器较明显,肺淤血、水肿、肝细胞脂肪变性、肾近曲小管上皮细胞变性、脑水肿等。病变程度与服药至死亡时间长短有关,中毒死亡与药物剂量、个体差异、所患疾病及中毒后抢救所致的临床并发症等因素有关。 This article analyzes the clinical symptoms of 6 cases of sedative hypnotics acute poisoning deaths, forensic autopsy and toxicology data. Sedative hypnotic drug poisoning clinical manifestations of coma, respiratory depression, hypotension, reflex disappeared around the circulatory failure. Pathological changes to lung, liver, kidney, brain and other organs more obvious pulmonary congestion, edema, fatty degeneration of hepatocytes, renal proximal tubule epithelial cell degeneration, cerebral edema and so on. The extent of the lesion was related to the length of time from taking medicine to death. The death due to poisoning was related to the dose of medicine, individual differences, the disease and the clinical complications caused by the rescue after poisoning.