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目的：证实脑梗塞能否引起心电图（ＥＣＧ）异常。方法：７０只Ｗｉｓｔａｒ鼠（雄３３，雌３７）分成对照组（２０）和模型组（５０），模型组制成不开颅的大脑中动脉（ＭＣＡ）供血区梗塞动物模型。动物麻醉后，用监护仪记录对照组和模型组手术前后的ＥＣＧ。结果：对照组手术前后ＥＣＧ正常。模型组ＭＣＡ阻塞前，所有动物ＥＣＧ正常，ＭＣＡ阻塞后２３只Ｗｉｓｔａｒ鼠出现ＥＣＧ异常，表现为ＳＴ段上抬（２３／５０），房扑（４／５０），频发室性早博（６／５０）。６５．２％的ＥＣＧ异常发生在ＭＣＡ阻塞后３ｈ内，最短为３５ｍｉｎ。结论：Ｗｉｓｔａｒ鼠ＭＣＡ阻塞后能引起ＥＣＧ异常。
Objective: To confirm whether cerebral infarction can cause electrocardiogram (ECG) abnormalities. Methods: Seventy Wistar rats (male 33 and female 37) were divided into control group (20) and model group (50). The model group was established as an infarcted animal model of non-cranial middle cerebral artery (MCA) supply. After the animals were anesthetized, ECGs of the control group and the model group before and after the operation were recorded with a monitor. Results: The control group had normal ECG before and after operation. All animals had normal ECG before MCA occlusion in the model group. ECG abnormalities occurred in 23 Wistar rats after MCA occlusion, showing ST-segment elevation (23/50), atrial flutter (4/50), frequent ventricular premature beats / 50). 65.2% of ECG abnormalities occurred within 3h after MCA occlusion, the shortest was 35min. Conclusion: MCA occlusion in Wistar rats can cause ECG abnormalities.