环丙沙星具有抗菌谱广、抗菌活性强、毒副反应较轻等特点.我科用于治疗呼吸道感染100例,获得良好效果.现报告如下.1 临床资料1.1一般资料100例中男65例,女35例,年龄17～80岁,平均38岁,治疗前发热、咳嗽、黄白痰,部分病人少量咯血、咽喉疼痛、肺部罗音及周围血白细胞增高.其中包括急性化脓性扁桃体炎4例,急性支气管炎5例,慢性支气管炎急性发作33例,肺炎41例,支气管扩张合并感染14例,支气管哮喘合并感染3例.所有病例均依据病史、症状、体征、X线胸片和实验室检查的结果为诊断依据.1.2病原菌全部病例于入院后及用环丙沙星之前先进行痰及咽喉分泌物细菌培养,于晨起嘱患者漱口后,将深吸气咳出的第二口痰送检.4例化脓性扁桃体炎用无菌棉签轻擦局部分泌物,放入干燥无菌试管送检.100例中有80例分离出致病菌,96例痰细菌培养阳性76例(6例为复数菌感染),4例扁桃体炎局部分泌物细菌培养均为阳性.分离出细菌106株.其中革兰阳性(G~+)球菌32株(32%),包括:金黄色葡萄球菌14株,表皮葡萄球菌8株,粪链球菌及肺炎链球菌各5株、革兰阴性(G~-)杆菌68株(68%),包括:绿脓杆菌20株,肺炎克雷白杆菌16株,大肠杆菌14 Ciprofloxacin has broad antibacterial spectrum, strong antibacterial activity, mild side effects and other characteristics of our department for the treatment of respiratory tract infection in 100 cases, and achieved good results. The report is as follows.1 Clinical data 1.1 General information 100 cases of male 65 Cases, female 35 cases, aged 17 to 80 years old, average 38 years old, before treatment fever, cough, yellow sputum, a small amount of hemoptysis in some patients, sore throat, lung rales and peripheral white blood cells increased, including acute suppurative tonsillitis 4 cases, acute bronchitis in 5 cases, acute exacerbation of chronic bronchitis in 33 cases, pneumonia in 41 cases, bronchiectasis with infection in 14 cases, bronchial asthma with infection in 3 cases.All cases were based on history, symptoms, signs, chest X-ray and The results of laboratory tests for the diagnosis based on 1.2 pathogenic bacteria in all cases after admission and ciprofloxacin sputum and throat secretions prior to bacterial culture in the morning Zhu Huanzhe patients mouthwash will be deep breathing cough Two sputum examination .4 cases of purulent tonsillitis with a sterile swab light rub local secretions, into a sterile sterile tube submission .100 cases of 80 isolated pathogens, 96 cases of sputum bacterial culture positive 76 Cases (6 cases of multiple bacterial infection), 4 cases 106 strains of bacteria were isolated, of which, 32 (32%) Gram-positive cocci (Staphylococcus aureus), including 14 strains of Staphylococcus aureus, 8 strains of Staphylococcus epidermidis, Streptococcus faecalis and Streptococcus pneumoniae 5, Gram-negative (G ~) 68 (68%), including: Pseudomonas aeruginosa 20, Klebsiella pneumoniae 16, Escherichia coli 14