Robust fault tolerant control for a class of time-delay linear systems with parameter uncertainties is studied, and a time-delay related state feedback control is proposed. On the basis of Lyapunov method , we prove that the proposed control law has integrity against sensor and/or actuator failures if the correspondent sufficient condition can be satisfied. A heuristic algorithm is also provided to facilitate the realization of the fault tolerant control. Finally, a simulation example is presented to show the effectiveness of the proposed approach . Robust fault tolerant control for a class of time-delay linear systems with parameter uncertainties is studied, and a time-delay related state feedback control is proposed. On the basis of Lyapunov method, we prove that the proposed control law has integrity against sensor and / or actuator failures if the correspondent sufficient condition can be satisfied. A heuristic algorithm is also provided to facilitate the realization of the fault tolerant control. Finally, a simulation example is presented to show the effectiveness of the proposed approach.