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目的 :分析前列地尔治疗高龄糖尿病并慢性肾脏病患者的临床效果和安全性。方法 :择取在我院接受糖尿病并慢性肾脏病治疗的且于2014年1月-2015年1月期间入院的患者76例,随机分组。结果 :治疗后,组间的ACR、UAER差异显著,p<0.05;LDL-c、CHOL差异不显著,p>0.05。患者均没有出现出血倾向、血管扩张反应以及过敏的不良反应。结论 :前列地尔治疗高龄糖尿病并慢性肾脏病患者的临床效果好,安全性高,值得推广应用。
Objective: To analyze the clinical effects and safety of alprostadil in the treatment of elderly patients with diabetes and chronic kidney disease. Methods: A total of 76 patients admitted to our hospital from January 2014 to January 2015 undergoing diabetes mellitus and chronic kidney disease were randomly assigned into groups. Results: After treatment, there were significant differences in ACR and UAER between the two groups (p <0.05). There was no significant difference in LDL-c and CHOL (p> 0.05). No bleeding tendency, vasodilatory reaction, and allergic adverse reactions were observed in all patients. Conclusion: Alprostadil is effective and safe in the treatment of elderly patients with chronic kidney disease. It is worth popularizing and applying.