成骨不全(Osteogenesis Imperfect a OI)为一古老遗传病,公元前1000年已有描述。近年来,国内对此病已多有报道,但此病在我国国内可能并不多见,据内蒙古医学院附属医院的调查,从1958年10月至1983年12月在该院住院的174077人中仅发现1例女性患者。本病分为两型先天性成骨不止(Osteogenesis Imperfect aCongenite)和迟发型成骨不全(Osteogenesis Imper-fect Tarde)。现将我们所发现的3例先天性成骨不全报道如下。 Osteogenesis (Osteogenesis Imperfect a OI) is an ancient genetic disease, described in 1000 BC. In recent years, there have been many reports about the disease in China, but the disease may not be seen in our country. According to the investigation of the Affiliated Hospital of Inner Mongolia Medical College, there were 174,077 hospitalized in the hospital from October 1958 to December 1983 Only one female patient was found. The disease is divided into two types of congenital osteoporosis (Osteogenesis Imperfect aCongenite) and delayed type osteosynthesis (Osteogenesis Imper-fect Tarde). Now we found three cases of congenital osteogenesis reported below.