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目的:观察清燥救肺汤加减联合西药治疗对反复呼吸道感染患儿血清免疫球蛋白及症状积分的影响。方法选取我院2013年1月~2016年1月132例反复呼吸道感染患儿为研究对象,将纳入患儿抽签随机分为中西医组(n=66)与常规治疗组(n=66)。常规治疗组给予对症治疗,给予玉屏风颗粒治疗;中西医结合组给予对症治疗,给予清燥救肺汤加减。比较两组的临床疗效、症状积分、免疫球蛋白指标、T淋巴细胞亚群。结果常规治疗组的治疗总有效率、症状积分、免疫球蛋白G(Ig G)、免疫球蛋白A(IgA)、CD_4~+、CD_4~+/CD_8~+分别为95.5%、(1.92±1.35)分、(9.36±1.28)g/L、(1.73±0.54)g/L、(45.53±8.24)%、(1.89±0.64)%与常规治疗组的84.8%、(3.06±1.38)分、(1.51±0.58)g/L、(8.22±1.35)g/L、(39.27±7.11)%、(1.33±0.78)%比较差异显著(P<0.05)。结论清燥救肺汤联合西药治疗反复呼吸道感染,可以提高免疫球蛋白水平,增强机体免疫功能,改善呼吸道感染症状。
Objective: To observe the effect of Qingzao Yifei Decoction combined with western medicine on serum immunoglobulin and symptom score in children with recurrent respiratory tract infection. Methods A total of 132 children with recurrent respiratory tract infections were selected from January 2013 to January 2016 in our hospital. Patients were randomly divided into two groups (n = 66) and conventional treatment group (n = 66). Conventional treatment group given symptomatic treatment, given Yupingfeng particles treatment; Integrative Medicine group symptomatic treatment given Qingzaojiu Tong decoction. The clinical efficacy, symptom score, immunoglobulin index and T lymphocyte subsets of the two groups were compared. Results The total effective rate, symptom scores, IgG, IgA, CD_4 ~ +, CD_4 ~ + / CD_8 ~ + of the conventional treatment group were 95.5%, 1.92 ± 1.35 ), (9.36 ± 1.28) g / L, (1.73 ± 0.54) g / L, (45.53 ± 8.24)%, (1.89 ± 0.64)% and the conventional treatment group 84.8%, (3.06 ± 1.38) 1.51 ± 0.58) g / L, (8.22 ± 1.35) g / L, (39.27 ± 7.11)% and (1.33 ± 0.78)%, respectively. Conclusion Qingzaojiu decoction combined with Western medicine in the treatment of recurrent respiratory tract infections can improve immunoglobulin levels, enhance immune function, and improve the symptoms of respiratory tract infection.