通过抑制DNA聚合酶可阻止DNA复制从而选择性地抑制恶性疟原虫增殖。真核生物DNA聚合酶分为9种,分别为α、β、γ、δ、ε、y、η、θ和ι。在恶性疟原虫中目前仅发现α、γ和δ,且γ存在于线粒体中。α和δ聚合 By inhibiting DNA polymerase can prevent DNA replication and thus selectively inhibit Plasmodium falciparum proliferation. Eukaryotic DNA polymerase is divided into 9 kinds, respectively, α, β, γ, δ, ε, y, η, θ and ι. Currently, only α, γ and δ are found in Plasmodium falciparum, and γ is present in mitochondria. α and δ polymerize