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作者对一组显微镜检查发现有红细胞渗出和血小板计数正常的88例(男46例,女42例)患者,进行了临床、组织学和免疫组织学等方面的研究和随访观察。结果为88例紫癜患者中,发现有两种不同的组织学反应型。第一型占27例,主要表现为嗜中性白细胞浸润和从水肿到纤维蛋白样坏死的血管壁损伤,称为多形核白细胞性血管炎(PMNV)。第二型包括61例主要表现为血管周围单一核细胞浸润,不累及浅部血管的管壁,称为淋巴细胞性血管周围炎(LP)。免疫组织学检查,在PMNV组的27例中,18例在血管壁发现有免疫球蛋白,16例在同一部位发现
The authors of a group of microscopic examination found erythrocyte leakage and platelet count in 88 cases (46 males and 42 females), clinical, histological and immunohistological aspects of the study and follow-up observation. The results of 88 cases of purpura patients, found that there are two different histological reaction type. The first type accounted for 27 cases, the main manifestations of neutrophil infiltration and from edema to fibrinous necrosis of the vascular wall damage, known as polymorphonuclear leukovascular (PMNV). The second type, including 61 cases of mainly perivascular mononuclear cells infiltration, not involving the shallow vessel wall, known as lymphocytic perivascular inflammation (LP). Immunohistological examination showed that in the 27 cases of PMNV group, 18 cases were found immunoglobulin in the vascular wall and 16 cases were found in the same site