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对肝病用药105例不良反应报告分析,结果显示:引起不良反应的药品涉及抗微生物药,生物制品、血制品、中草药制剂、氨基酸注射液等27种药品,其中促肝细胞生长素17例,占全部报告的16.2%;以给药途经分,静脉给药反应90例,占全部报告的85.7%;反应症状最多的是输液样反应,其次为过敏性皮疹;反应症状最严重的药是酮康唑,提示肝病用药应考虑肝脏清除药物的能力。
Drug adverse reactions reported in the analysis of 105 cases of liver disease drug use, the results showed: adverse drug reactions involving antimicrobial drugs, biological products, blood products, herbal preparations, amino acids injection of 27 kinds of drugs, including hepatocyte growth hormone in 17 cases, accounting for All reported 16.2%; to the way of administration through the points, intravenous administration of 90 cases, accounting for 85.7% of all reports; reaction symptoms are the most infusion-like reactions, followed by allergic skin rash; the most serious symptoms of the reaction Ketoconazole drug, suggesting that liver disease medication should consider the ability of the liver to clear drugs.