铜蓝蛋白具有亚铁氧化酶活性,能转运铜,并在维持肝铜的内环境稳定中起重要作用。近来有报告表明,铜蓝蛋白不但是一种强有力的脂类自身氧化抑制剂,而且能歧化过氧化物基团,是血清中过氧化物阴离子基团的清除剂。最近作者发现铜蓝蛋白还具有中和“毒性激素”和抗肿瘤的作用。早在四十年代末,Nakahara等报告自恶性肿瘤组织中分离出一种成份,给小鼠注射后,在24小时内引起肝过氧化氢酶活性下 Ceruloplasmin has ferric oxidase activity, can transport copper, and plays an important role in maintaining the internal environment of liver copper. Recently, it has been reported that ceruloplasmin is not only a potent lipid auto-oxidation inhibitor but also a disproportionation of peroxide groups and is a scavenger of peroxide anionic groups in serum. The authors recently discovered that ceruloplasmin also neutralizes “toxic hormones” and anti-tumor effects. As early as the end of the 1940s, Nakahara et al. reported that a component isolated from malignant tumor tissues was injected into mice and caused the activity of liver catalase within 24 hours after injection.