1病例和方法１２例肾移植病人，移植后３个月，在由环抱素Ａ换为硫唑嘌呤治疗前即刻及换用硫咄瞟吟后第１周、第２周、第４周分别检测肾功能参数，另外指定９例在此段时间继续用环孢素Ａ，作为对照组。2结果停用环抱素Ａ１周后，肾小球流过率（ＧＦＲ）明显上升（ＧＦＲ１５± 1 cases and methods of 12 cases of renal transplant patients, 3 months after transplantation, from the ring for the conversion of azathioprine A treatment immediately before and after switching to Sulfur abuse Tune 1 week, 2 weeks, 4 weeks were detected Renal function parameters, another designated 9 cases continue to use cyclosporine A during this period, as a control group. 2 Results cessation of ciliary hormone A1 week, glomerular flow rate (GFR) increased significantly (GFR15 ±