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对应用顺铂、阿霉素为主进行化疗的６６例恶性肿瘤患者，分别采用康泉（３２例）和枢复宁（３４例）联合胃复安、苯海拉明作为止吐剂控制恶心呕吐反应，结果发现康泉组对急性呕吐反应的控制明显优于枢复宁组。第１天控制呕吐的有效率（ＣＲ＋ＰＲ）分别为９６％和８０％，控制恶心的有效率（ＣＲ＋ＰＲ）分别为９４％和７７％，两组比较Ｐ＜０．０５。两组对延缓期（２～５天）呕吐反应的疗效无统计学差别。两组副反应均轻微。本文提示单剂量康泉或枢复宁联合胃复安、苯海拉明控制化疗引起的急慢性呕吐反应疗效满意，而对重度急性呕吐反应的控制单剂量康泉优于单剂量枢复宁。
66 cases of malignant tumor patients treated with cisplatin and adriamycin were treated with Kangquan (32 cases) and Shufuning (34 cases) combined with metoclopramide and diphenhydramine as antiemetics to control nausea Vomiting reaction, the results found Kangquan group of acute vomiting response was significantly better than the pivoting Ning group. The effective rate of vomiting (CR + PR) on day 1 was 96% and 80% respectively, and the effective rate of nausea control (CR + PR) was 94% and 77%, respectively. There was no statistical difference between the two groups in the response to vomiting during the latencies (2 to 5 days). Side effects were minor in both groups. This article suggests that a single dose of Kangquan or Shufining combined with metoclopramide and diphenhydramine in response to acute and chronic vomiting induced by chemotherapy is effective, while the control of severe acute vomiting single dose of kangquan is better than a single dose of pentobarbital.