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米槁心乐滴丸是由米槁精油、冰片等制成的中药复方制剂。本研究在离休豚鼠Langedorff氏心脏灌流装置上,观察米槁心乐滴丸对冠脉流量、心率和心肌收缩力的影响;在垂体后叶素致豚鼠急性心肌缺血模型上观察米槁心乐对肢体回导联心电图(ECG)ST段的影响。结果表明,该药能增加离体心脏冠脉流量、减慢心率、降低心肌收缩力,能明显对抗ECGSTR的缺血性改变。提示,米槁心乐滴丸具有抗心肌缺血作用。
Mi Fu Xinle Drop Pill is a Chinese herbal compound preparation made from rice bran oil and borneol. This study was conducted on a Langedorff cardiac perfusion device in a retired guinea pig to observe the effect of Miqixinleji on coronary flow, heart rate, and myocardial contractility; observation of Miqixinle on limbs in a model of acute myocardial ischemia induced by pituitrin on guinea pigs Return ECG ST segment effects. The results showed that the drug can increase coronary flow in isolated hearts, slow down the heart rate, reduce myocardial contractility, and can significantly counteract the ischemic changes of ECGSTR. Tips, Mi Fu Xinle Drop Pills have anti-ischemic effect.