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来自丹麦、瑞士和美国的报道表明,近30年来肛门癌的发生率明显增加,其增加明显程度女性高于男性,这些趋势表明,AIDS流行之前,生物特性和环境就发生了重大变化。为了探讨AIDS流行与肛门癌发生之间的可能存在的关系,丹麦流行病学中心和美国NCI分析了AIDS与癌症监视系统的最新统计资料。 从859 398例癌症报告和50 050例AIDS报告中,筛选出39例患有表皮样肛门直肠癌的AIDS病人,31例为肛门癌,8例为肛门直肠癌,其中3例癌诊断先于AIDS诊断5年以上。另有21例肛门部位的其它类型肿瘤包括在内,
Reports from Denmark, Switzerland, and the United States indicate that the incidence of anal cancer has increased significantly in the past 30 years. The increase in the incidence of anal cancer is higher in women than in men. These trends indicate that before the AIDS epidemic, major changes in biological characteristics and the environment have occurred. To explore the possible relationship between the AIDS epidemic and the development of anal cancer, the Danish Epidemiology Center and the NCI of the United States analyzed the latest statistics on AIDS and cancer surveillance systems. From 859,398 cancer reports and 50,050 AIDS reports, 39 cases of AIDS patients with epidermoid anorectal cancer were screened out. 31 cases were anal cancer, 8 cases were anal rectal cancer, and 3 cases had cancer diagnosis prior to AIDS. Diagnosis more than 5 years. Another 21 cases of other types of tumors in the anal area were included.