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目的探讨早期应用美皮康联合美清佳预防盐酸胺碘酮(商品名:可达龙)外周静脉输注所致静脉炎的临床效果。方法选取外周静脉输注可达龙的患者100例,在患者知情同意的情况下采用随机数字法将患者分为研究组与对照组,每组各50例。研究组使用美皮康及美清佳干预,对照组应用50%葡萄糖水20 m L+地塞米松5 mg浸湿无菌纱布后持续湿敷至输液结束。2组分别于干预后第1、2、3天观察静脉炎发生率及严重程度,评价应用效果。结果预防措施实施3 d后,对照组静脉炎发生率及严重程度明显高于研究组(P=0.032),研究组预防效果优于对照组。结论美皮康联合美清佳预防可达龙外周静脉输注所致静脉炎的效果显著,可明显减少外周静脉炎的发生率,静脉炎严重程度大大降低,可在临床应用推广。
Objective To investigate the clinical effect of early application of Mepikang combined with Membrane to prevent phlebitis induced by peripheral intravenous infusion of amiodarone hydrochloride (trade name: Reach Dragon). Methods A total of 100 patients with peripheral venous infusion of Dulong were selected. Patients were divided into study group and control group with 50 patients in each group with informed consent. The study group was treated with meperidine and meclofenamate. The control group was treated with 20 m L of dexamethasone 50 mg dexamethasone 5 mg soaked in sterile gauze, and then continuously wet-applied to the end of infusion. The incidences and severity of phlebitis in the two groups were observed on days 1, 2 and 3, respectively, to evaluate the application effect. Results After 3 days of preventive measures, the incidence and severity of phlebitis in the control group were significantly higher than those in the study group (P = 0.032). The preventive effect of the study group was superior to that of the control group. Conclusion The combination of mepiquamil and mefloxacin can prevent phlebitis induced by peripheral vein infusion of galactocene significantly, and can significantly reduce the incidence of phlebitis. The severity of phlebitis is greatly reduced and can be popularized in clinical application.