生物技术给治疗癌症的几种免疫疗法增添或注入了新的生命,而使旧的免疫疗法相形见拙,但旧法重新引起人们的兴趣,即用全瘤细胞或部分瘤细胞刺激病人的免疫系统来破坏癌瘤。这种“癌疫苗”将象狂犬病疫苗一样,作为一种治疗方法,而不是预防。尽管某些疫苗的研制者认为,他们的疫苗对某些高危组的病人可能有预防癌症的作用。以前研制癌症疫苗的工作不很成功。但在抗原鉴定、提纯及表达的生物技术方面有改进,因此,使免疫疗法获得了新生。在研制有效的癌症疫苗中,主要的问题是识别特异的肿瘤相关抗原(TAA),它能使免疫系统破环癌细胞,而不伤害正常组织。这是一个很 Biotechnology adds or injects new life into several immunotherapy treatments for cancer, and dwarfs old immunotherapy, but the old method has rekindled interest in using whole tumor cells or some tumor cells to stimulate the patient’s immune system. To destroy cancerous tumors. This “cancer vaccine” will be treated like a rabies vaccine as a treatment rather than a prevention. Although some vaccine developers believe that their vaccine may have a role in cancer prevention in some high-risk groups. Previous work to develop cancer vaccines was not very successful. However, there have been improvements in the biotechnologies of antigen identification, purification, and expression, and therefore, new immunotherapy has been achieved. In the development of effective cancer vaccines, the main problem is the identification of specific tumor-associated antigens (TAA), which can cause the immune system to destroy cancer cells without harming normal tissues. This is a very