神经损害是麻风病理学和临床表现的基本特征,起因于麻风杆菌和神经内宿主细胞之间的相互作用。麻风杆菌或其如何侵入神经,至今仍不很清楚。为更好地了解和处理本病,这无疑是一个主要的问题。麻风杆菌侵入神经的可能途经包括:a.许旺氏鞘(Schwann)细胞通路,这种细胞复盖在真皮乳头层中的神经纤维末梢,而不包含在神经束膜鞘之内;b.通过神经束膜 Nerve damage is a fundamental feature of leprosy pathology and clinical manifestations, resulting from the interaction between Leprosy and neuronal host cells. Leprosy or how it invades the nerves is still not very clear. This is undoubtedly a major issue for better understanding and handling of the disease. Possible routes of Leprosy invasion into nerves include: a. Schwann cell pathways that cover the nerve fiber tip in the dermal papilla layer and are not contained within the perineurium; b. Passage through Neural bundle