本文主要研究P物质(substance P,SP)免疫反应神经纤维与猴垂体前叶促甲状腺素(thyroid stimulating hormone,TSH)细胞和促皮质素(ACTH)细胞之间的关系。恒河猴垂体前叶切片分别用抗SP和抗TSH,或抗SP与抗ACTH抗体双标记染色。研究中出现SP免疫反应神经纤维与TSH、ACTH细胞非常接近。结果提示,SP能神经纤维可能直接支配TSH或ACTH细胞,并可能参与其分泌的调节。 This article mainly studies the relationship between substance P (SP) -induced nerve fibers and thyroid stimulating hormone (TSH) cells and corticotropin (ACTH) cells in the anterior pituitary of monkeys. Rhesus anterior pituitary sections were stained with anti-SP and anti-TSH, or anti-SP and anti-ACTH antibodies, respectively. In the study, SP immunoreactive nerve fibers appeared to be very similar to TSH and ACTH cells. The results suggest that SP nerve fibers may directly control TSH or ACTH cells, and may participate in the regulation of its secretion.