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目的调查新疆地区维吾尔族成年人颈动脉粥样硬化(CAS)的患病率及相关因素,为今后动脉粥样硬化的防治提供基础资料。方法四阶段整群随机抽样法,在新疆的7个地区抽取年龄在35岁以上维吾尔族样本4 352例,进行颈动脉超声及生化指标的测定,统计维吾尔族成年人CAS的患病率,并对CAS的相关因素进行Lo-gistic回归分析。结果新疆维吾尔族成年人CAS的患病率为30.9%,其中单纯颈动脉内膜中层厚度(IMT)增厚者占18.4%,非狭窄性斑块者占11.1%,狭窄性斑块者占1.4%。CAS发病的影响因素为男性、年龄、吸烟、高血压、糖尿病、代谢综合征、高TC血症、高TG血症、高尿酸血症。结论新疆维吾尔族成年人的CAS的患病率较高,男性、年龄、吸烟、高血压、糖尿病、代谢综合征、高TC血症、高TG血症及高尿酸血症等因素可能为新疆维吾尔族成年人CAS的独立危险因素。
Objective To investigate the prevalence and related factors of carotid atherosclerosis (CAS) in Uygur adults in Xinjiang and provide the basic data for the prevention and treatment of atherosclerosis in the future. Methods A four-stage cluster random sampling method was used to collect 4 352 Uygur samples aged over 35 from 7 districts in Xinjiang. The carotid artery ultrasound and biochemical indexes were measured and the prevalence of CAS in Uygur adult adults was calculated. Lo-gistic regression analysis of CAS related factors. Results The prevalence of CAS in adult Uygur adults in Xinjiang was 30.9%, of which 18.4% were carotid intima-media thickness (IMT) thickening, 11.1% were non-stenotic plaques and 1.4 were stenotic plaques %. CAS incidence of factors affecting men, age, smoking, hypertension, diabetes, metabolic syndrome, hypercholesteremia, hypercholesterolemia, hyperuricemia. Conclusion The prevalence of CAS in Uighur adults in Xinjiang is high, and the factors such as male, age, smoking, hypertension, diabetes mellitus, metabolic syndrome, hypercholesteremia, hypercholesteremia and hyperuricaemia may be Xinjiang Uighur Family adult CAS independent risk factors.