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目的:探讨新生儿脑室内出血(IVH)的发病机理、预后与CT分级的关系,评价其CT诊断及随访价值。方法: 60例经CT诊断为IVH患儿,早产儿19例,足月儿41例,生后1周内作首次头颅CT扫描,1个月后进行CT随访观察。结 果:CT表现为不同程度的IVH,侧脑室内出血59例,侧脑室及第三脑室内出血1例;室管膜下出血(SEH)18例,早产儿12 例;脉络丛出血24例,足月儿19例;侧脑室轻度扩大11例,急性梗阻性脑积水4例;脑实质内出血(ICH)11 例,硬膜下血肿 (SDH)3例,蛛网膜下腔出血(SAH)49例,缺氧缺血性脑病(HIE)46例。根据有无侧脑室扩大及ICH,将本组新生儿IVH分 为3级:Ⅰ级单纯IVH45例;Ⅱ级IVH伴侧脑室扩大10例;Ⅲ级IVH伴侧脑室扩大、ICH5例。随访中,19例出现后遗CT改 变:Ⅰ级5例,均为侧脑室轻度扩大;Ⅱ级9例,侧脑室轻度扩大5例,梗阻性脑积水4例;Ⅲ级5例,侧脑室轻度扩大1例, 梗阻性脑积水3例,脑萎缩3例,脑软化灶4例。结论:Ⅰ级IVH预后良好;Ⅱ、Ⅲ级IVH预后较差。因此头颅CT扫描在新 生儿IVH诊断及预后判断方面有重要价值。
Objective: To explore the pathogenesis of neonatal intraventricular hemorrhage (IVH), the relationship between prognosis and CT grade, evaluate the CT diagnosis and follow-up value. Methods: Sixty children with IVH diagnosed by CT, 19 preterm infants and 41 full term infants were diagnosed by CT. The first CT scan was performed within 1 week after birth. CT was followed up one month later. Results: CT showed different degrees of IVH, 59 cases of lateral ventricular hemorrhage, 1 case of lateral and third ventricular hemorrhage; 18 cases of subependymal hemorrhage (SEH), 12 cases of premature neonates; 24 cases of choroid plexus hemorrhage, (N = 19), mild lateral enlargement in 11 cases, acute obstructive hydrocephalus in 4 cases, intracerebral hemorrhage (ICH) in 11, subdural hematoma (SDH) in 3 and subarachnoid hemorrhage (SAH) in 49 , Hypoxic-ischemic encephalopathy (HIE) in 46 cases. According to the presence or absence of lateral ventricle expansion and ICH, the group of newborn IVH is divided into three levels: Ⅰ grade simple IVH45 cases; Ⅱ grade IVH with lateral ventricle enlargement; Ⅲ grade IVH with lateral ventricle expansion, ICH5 cases. In the follow-up, 19 cases had posterior subsidence CT changes: 5 cases of grade Ⅰ were mild ventricular enlargement in 9 cases, 9 cases of grade Ⅱ, 5 cases of lateral ventricle slight enlargement, 4 cases of obstructive hydrocephalus, 5 cases of grade Ⅲ, One case of lateral ventricle was mildly enlarged, 3 cases of obstructive hydrocephalus, 3 cases of brain atrophy, 4 cases of cerebral softening. Conclusions: The prognosis of grade Ⅰ IVH is good. The prognosis of grade Ⅱ and Ⅲ IVH is poor. Therefore, cranial CT scan in the diagnosis of neonatal IVH and prognosis have important value.