采用重组干扰素α－2b（IFNα－2b）、重组干扰素α1（IFNα1）、干扰素α－nl（IFNα－nl）治疗慢性乙型肝炎（3×106IU／d用7天，继以3×106IU每周3次肌注，总疗程3个月）；慢性丙型肝炎（3×106IU／d用10天，继以3×106IU每周3次肌注，总疗程6个月）。治疗开始1周内副作用主要表现为发热、头痛、肌肉关节酸痛等流感样症状，白细胞减少、脱发、失眠、焦虑及消化道副反应主要见于治疗后数周。上述不良反应患者均能耐受，一般无需中止治疗。 Chronic hepatitis B was treated with recombinant interferon α-2b (IFNα-2b), interferon α1 (IFNα1) and interferon α-nl (3 × 106 IU / d for 7 days followed by 3 × 106IU intramuscular injection 3 times a week, the total course of 3 months); chronic hepatitis C (3 × 106IU / d with 10 days, followed by 3 × 106IU intramuscularly 3 times per week, the total course of 6 months). Side effects during the first week of treatment were mainly fever, headache, muscle and joint flu and other flu-like symptoms, leukopenia, hair loss, insomnia, anxiety and gastrointestinal side effects mainly seen in the weeks after treatment. The above adverse reactions can tolerate patients, usually without stopping treatment.