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肾素-血管紧张素-醛固酮的生化代谢系统(R-A-A系统)是血压控制机理的分子基础之一,自六十年代末起对肾素抑制剂已进行了较多的研究。我们曾报道合成了一系列由Statine及其类似物取代的底物四肽类肾
The renin-angiotensin-aldosterone biochemical metabolic system (R-A-A system) is one of the molecular bases for the mechanism of blood pressure control and much research has been done on renin inhibitors since the late 1960s. We have reported the synthesis of a series of substrate tetrapeptides called Statine and its analogues