作者研究组胺对中耳粘膜纤毛运动功能的影响,取体重250g的豚鼠50只,每只从一侧中耳两处取粘膜片,一处接近另一处远离咽鼓管鼓室口。将粘膜片进行组织培养。以光电法测定纤毛运动频率,分别测定给药前及灌注组胺及苯海拉明或甲氰咪胍后纤毛运动频率。结果:近口处粘膜灌流组胺15分钟后,组胺浓度 The study of histamine on the middle ear mucosal ciliary motor function, take a body weight of 250g guinea pigs 50, each from one side of the middle ear to take mucosa, one near the other away from the eustachian tube tympanic cavity mouth. Mucosal tissue culture. The frequency of ciliary movement was measured by the photoelectrochemical method. The ciliary motility was measured before administration and after histamine infusion and diphenhydramine or cimetidine. Results: Near the mouth mucosal perfusion histamine after 15 minutes, histamine concentration