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目的:观察并比较丁二磺酸腺苷蛋氨酸、门冬氨酸钾镁两种药物在治疗妊娠合并乙型慢性肝炎高黄疸中的临床效果。方法:选择70例我院于2014年10月至2015年11月接收的乙型慢性肝炎高黄疸患者作为研究对象,将其随机分为研究组与参照组,各35例。两组均采用还原型谷胱甘肽、甘草酸苷进行治疗,研究组在此基础上使用丁二磺酸腺苷蛋氨酸进行治疗,参照组在此基础上使用门冬氨酸钾镁进行治疗,对比两组患者的治疗效果。结果:研究组的肝功能各项指标、孕产妇与围产儿的结局均优于参照组,且差异具有统计学意义(P<0.05)。结论:丁二磺酸腺苷蛋氨酸在妊娠合并乙型慢性肝炎高黄疸的治疗上具有显著的效果,能有效改善患者症状,促进患者康复,值得推广。
Objective: To observe and compare the clinical effects of adenosine methionine butadionate and potassium magnesium aspartate in the treatment of high-risk jaundice of pregnancy complicated with chronic hepatitis B in pregnancy. Methods: Seventy patients with chronic hepatitis B in jaundice from October 2014 to November 2015 in our hospital were selected as study subjects, and randomly divided into study group and reference group with 35 cases each. Both groups were treated with reduced glutathione and glycyrrhizin. On the basis of this study, the research group used adenosine methionine buthionate to treat the patients. On the basis of this, the reference group treated with potassium and magnesium aspartate, Compare the treatment effect of two groups of patients. Results: All indexes of liver function, maternal and perinatal outcomes in the study group were better than the reference group, and the difference was statistically significant (P <0.05). Conclusion: The adenosine methionine succinate has a significant effect on the treatment of high-risk jaundice in patients with chronic hepatitis B during pregnancy. It can effectively improve the symptoms and promote the recovery of patients and is worth promoting.