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应用现在的治疗方案,80％以上的何杰金病病人能得到有效的治疗。早期病人用扩大野照射有90％的治愈率,但考虑到其致命的远期效应,很多研究组改用温和的化疗加累及野照射;中期的综合治疗中目前也不用扩大野照射;晚期的治疗较复杂,新的、高剂量BEACOPP方案的使用显著地改善了预后;对于复发的早期病人,在联合化疗失败时可考虑高剂量化疗加自体干细胞移植。
With the current treatment program, more than 80% of patients with Hodgkin’s disease can receive effective treatment. The early patients had a 90% cure rate with expanded wild-type radiation, but given their fatal long-term effects, many research groups switched to mild chemotherapy plus invasive irradiation; in the mid-term comprehensive treatment, there is currently no need to expand wild radiation; The treatment is complex and the use of the new, high-dose BEACOPP regimen significantly improves the prognosis; for early relapse patients, high-dose chemotherapy plus autologous stem cell transplantation may be considered when combination chemotherapy fails.