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目的:观察桂枝茯苓丸辨证加减联合米非司酮治疗子宫肌瘤的临床疗效。方法 :将94例子宫肌瘤分为观察组与对照组,对照组给予米非司酮治疗,观察组在对照组治疗基础上给予桂枝茯苓丸辨证加减治疗。结果:2组治疗前后子宫体积、肌瘤体积比较,差异均有统计学意义(P<0.05);治疗后,观察组子宫体积、肌瘤体积与对照组比较,差异均有统计学意义(P<0.05)。2组治疗前后LH、E2、FSH、P比较,差异均有统计学意义(P<0.05);治疗后,观察组LH、E2与对照组比较,差异均有统计学意义(P<0.05)。复发率对照组31.9%,观察组6.4%,2组比较,差异有统计学意义(P<0.05)。结论:桂枝茯苓丸辨证加减联合米非司酮治疗子宫肌瘤的临床疗效显著,能够改善患者的临床症状,提高患者的生活质量,且复发率低。
Objective: To observe the curative effect of Guizhi Fuling pill combined with mifepristone in the treatment of uterine fibroids. Methods: 94 cases of uterine fibroids were divided into observation group and control group, the control group was treated with mifepristone, and the observation group was given Guizhi Fuling pill based on the treatment group. Results: The uterine volume and fibroid volume before and after treatment in both groups were significantly different (P <0.05). After treatment, the volume of uterus and the fibroid volume in the observation group were significantly different from those in the control group (P <0.05). There were significant differences in LH, E2, FSH and P between the two groups before and after treatment (P <0.05). After treatment, LH and E2 in the observation group were significantly different from those in the control group (P <0.05). The recurrence rate was 31.9% in the control group and 6.4% in the observation group. There was significant difference between the two groups (P <0.05). Conclusion: The clinical curative effect of Guizhi Fuling pill combined with mifepristone in the treatment of uterine myoma is significant, which can improve the clinical symptoms and improve the quality of life of patients with low recurrence rate.