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目的探讨新生儿期食管闭锁手术治疗与儿童型功能性胃肠病的关系。方法 26例食管闭锁手术后患儿(手术组)、28例体检健康儿童(对照组),均应用小儿胃肠症状问卷调查和RomeⅢ诊断标准进行胃肠道症状评估。结果手术组5例,对照组4例患儿有儿童型功能性胃肠病,2组发生率比较差异无统计学意义(P>0.05);手术组吞咽困难和/或环咽部运动障碍发生率高于对照组(P<0.05);食管闭锁患儿出生体质量、鼻饲时间、NICU住院时间、合并其他先天畸形、术后并发症是发生儿童型功能性胃肠病的危险因素(P<0.05)。结论 新生儿期手术创伤治疗食管闭锁患儿是发生功能性胃肠病的危险因素。
Objective To explore the relationship between neonatal esophageal atresia surgery and children with functional gastrointestinal disease. Methods Twenty-six children with esophageal atresia (surgery group) and 28 healthy children (control group) were enrolled in the study. Gastrointestinal symptoms were evaluated by questionnaire of gastrointestinal symptoms in children and Rome Ⅲ diagnostic criteria. Results There were 5 cases of operation group and 4 cases of children with functional gastrointestinal disease in control group. There was no significant difference in incidence between the two groups (P> 0.05). The dysphagia and / or circulatory dysfunction (P <0.05). The birth weight, nasal feeding time, NICU length of hospital stay, and other congenital malformations in children with esophageal atresia were significantly higher than those in the control group (P <0.05). Postoperative complications were the risk factors for children with functional gastrointestinal disease (P < 0.05). Conclusion The surgical treatment of neonatal period trauma patients with esophageal atresia is a risk factor for functional gastrointestinal disease.