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采用放射免疫法,测定天花粉和利凡诺尔中期引产前后,母血与羊水中人绒毛膜促性腺激素(HCG)、雌二醇、雌三醇、孕酮、皮质醇和催乳素浓度的变化,结果表明:(1)天花粉引产过程中,母血浆HCG 的下降速度较雌二醇、雌三醇和孕酮为快,但与引发流产的时间无显著关联,它们的相关系数分别为0.52,-0.20,-0.07和0.07(P>0.05)。(2)利凡诺尔引产过程中,母血浆HCG 的下降速度与雌二醇、雌三醇和孕酮的下降率并无显著差异(P>0.05),且四种激素的下降速度均较慢。(3)两种引产过程中羊水雌二醇和皮质醇均有显著升高(P<0.01)文中对天花粉和利凡诺尔中期引产的机理提出进一步探讨,为寻找更有效的抗早孕方法提供了理论依据。
Radioimmunoassay was used to determine the changes of concentrations of human chorionic gonadotropin (HCG), estradiol, estriol, progesterone, cortisol and prolactin in maternal blood and amniotic fluid before and after induction of labor by TCS and Rivanol The results showed that: (1) The plasma HCG descended faster than that of estradiol, estriol and progesterone during the process of labor induction, but there was no significant correlation with the time of inducing abortion. The correlation coefficient of HCG of them was 0.52, -0.20, -0.07 and 0.07 (P> 0.05). (2) There was no significant difference (P> 0.05) in the declining rate of HCG in estanilol and estrogen, estriol and progesterone during the induction of labor in Rivanol, and the decreasing rate of all four hormones was slower. (3) Both amniotic fluid estradiol and cortisol were significantly increased in both induced abortion (P <0.01) .This paper further explored the mechanism of TC and Richenor mid-term induction of labor and provided the theory for finding more effective anti-abortion methods in accordance with.