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通过前瞻性地观察 ２００ 例临床疑为头颈部肿瘤的患者，最终诊断出 ９４ 例原发性和 ５６ 例复发性鳞细胞癌（ Ｓ Ｃ Ｃ），３ 例原发性和 ７ 例复发性囊腺癌（ Ａ Ｃ Ｃ），６ 例非何杰金氏淋巴瘤，１０ 例远端转移癌，６例其它恶性肿瘤，１０ 例炎症和 ８ 例其它非恶性情况。方法：在相同的条件下采集骨显像和９９ｍ Ｔｃ Ｍ Ｉ Ｂ Ｉ显像，之后分别判断和叠加后判断，并与活检、手术和 Ｃ Ｔ 结果相对比。结果：９９ｍ Ｔｃ Ｍ Ｉ Ｂ Ｉ对肿瘤检出的灵敏度和特异性分别是９０％ 和 ７８％ ，对鉴别恶性淋巴瘤的灵敏度和特异性分别是 ９０％ 和 ９５％ （ Ｃ Ｔ： ７９％ 和 ６６％ ，９０％ 和 ７９％ ）。在复发 Ｓ Ｃ Ｃ 和 Ａ Ｃ Ｃ 亚组中，９９ｍ Ｔｃ Ｍ Ｉ Ｂ Ｉ探测肿瘤的灵敏度和特异性分别是 ９５％ 和７１％ ，而 Ｃ Ｔ 为７８％ 和６８％ 。单独骨 Ｓ Ｐ Ｅ Ｃ Ｔ 检出转移性骨肿瘤的灵敏度和特异性分别为 １００％ 和１７％ 。９９ｍ Ｔｃ Ｍ Ｉ Ｂ Ｉ和骨 Ｓ Ｐ Ｅ Ｃ Ｔ 显像融合，鉴别出局部骨浸润和骨炎症，并在初期骨病变中使骨 Ｓ Ｐ Ｅ Ｃ Ｔ的特异性提高到１００％ 。肿瘤大小、分期、组织学和预先治疗对示踪剂的摄取或扫描的诊断作用无统计学上的影
By prospectively observing 200 patients with clinically suspected head and neck cancer, 94 patients with primary and 56 recurrent squamous cell carcinoma (SCC) were diagnosed, and 3 patients with primary and 7 recurrent cysts Adenocarcinoma (A C C), 6 non-Hodgkin’s lymphoma, 10 distal metastases, 6 other malignancies, 10 inflammation and 8 other non-malignant cases. Methods: Bone imaging and 99m Tc-M I B I imaging were performed under the same conditions, and then judged separately and superimposed, and compared with biopsy, surgery and C T results. RESULTS: The sensitivity and specificity of 99m Tc-M I B I for detecting tumors were 90% and 78%, respectively, and the sensitivity and specificity for distinguishing malignant lymphomas were 90% and 95% (C T: 79% and 66%, 90% and 79%). In the recurrence S C C and A C C subgroups, the sensitivity and specificity of 99m Tc-M I B I detection of tumors were 95% and 71%, respectively, while C T was 78% and 68%, respectively. The sensitivity and specificity of individual bone S P E C T in detecting metastatic bone tumors were 100% and 17%, respectively. 99m Tc-M I B I and S P E C T scintigraphic fusion to identify local bone infiltration and osteoarthritis and to increase bone SPECT specificity to 100% in primary bone lesions. Tumor size, staging, histology, and pre-treatment did not have a statistically significant effect on the uptake or scanning of tracer