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3例急性淋巴细胞性白血病患者获得完全缓解(CR)后,外周骨髓仍存在未被抑制的局限性活性骨髓灶,骨髓细胞学检查表明常规穿刺部位的骨髓均呈CR髓像,但在局限性活性骨髓灶含有超过5%的幼淋白血病细胞,确定为骨髓残余白血病病灶,这与通常所指弥散分布于全身的白血病细胞而言的残余白血病系两个不同的概念。这是迄今为止首次发现的局限性骨髓残余病灶。这将对探讨白血病缓解的标准,制订治疗方案及判定预后具有意义。
In 3 cases of acute lymphoblastic leukemia patients with complete remission (CR), peripheral bone marrow still exist unrestricted active bone marrow lesions, bone marrow cytology examination showed that the conventional puncture site of bone marrow showed CR medullary, but in the limitations Active bone marrow foci contain more than 5% of leukemia cells identified as a myeloid leukemia lesion, which is two different concepts of residual leukemia that are commonly referred to as lentiformly spread throughout the body. This is the first time to find the limitations of residual marrow lesions. This will be of great significance in exploring the criteria for the remission of leukemia, in developing treatment options and in determining the prognosis.